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Why it matters
Grant funded research
Ensures credibility, financial backing.
IRB Approved
Protects participant safety and ethics.
Double blind, Placebo controlled
Eliminates bias, ensures objectivity.
Independent, Randomized
Enhances validity, reduces confounding.
Cross-over clinical trial
Increases reliability, reduces variability.
Peer-Reviewed
Validates quality, expert scrutiny.
Published in Medical Journals
Widens credibility, professional dissemination.
Pharmacy Level Grade Clinical Research
High standard, rigorous testing.
INDEPENDENT, GRANT FUNDED STUDY
The Background
In 2019, the University of the Pacific led a clinical trial with the innovative Clinical and Outcomes Research (iCOR) lab at the Thomas J. Long School of Pharmacy and Health Sciences.
Pharmacy Level Grade Clinical Research
The Study
Nine participants completed the study. AHS scores increased from baseline to 7 AM by 4.11 ± 3.17 and 1.26 ± 2.29 for the placebo and active arms respectively (P = .16). AHS headache scores increased from baseline to 7 AM by 2.44 ± 1.67 and 1.11 ± 1.17 for the placebo and active arms respectively (P = .06). AHSS scores increased from baseline to 7 AM by 1.0 ± 1.05 and 0.41 ± 1.08, for the placebo and active arms respectively (P = .30). There was no significant difference between average BrAC at 7 AM between the placebo and active arms.
Randomized, double-blind, Placebo controlled
The Method
This was a randomized, double-blinded, placebo-controlled, crossover pilot study. Healthy volunteers of 21- to 40-year-olds were eligible for participation and received either the actual product or a placebo on two different occasions.
Participants were given 43 mL of whiskey every twenty minutes for up to 3 hours to achieve a blood alcohol concentration (BrAC) ≥ 0.12%. Hangover severity was assessed using the Acute Hangover Scale (AHS) and Acute Hangover Severity Scale (AHSS) validated tools.
Proven effectiveness
The Results
The Hangover Secret (our old company name) showed “positive signals in the prevention of alcohol-induced hangover, especially headaches”
The improvements that participants say, surpassed the minimum clinically significant difference in overall AHS score and three individual AHS symptoms scores (hangover, headache, and thirst).
Comments from the research team:
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Sheel Patel, PharmD
"Independent of the validated tools we used, there were visible improvements in participants' symptoms and behavior some mornings after. After being unblinded, we found that most of those mornings were after consuming The Hangover Secret."
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Der Yu Wang, PharmD
"We are on to something as this was a well-designed, placebo-controlled clinical trial. We only have supportive care to help with hangovers and I believe this is the product that people are looking for."
